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| 介入治疗对肝细胞癌层粘连蛋白表达的影响 | |
| 引用本文： | 肖恩华,胡国栋,刘鹏程,胡道予,刘绍春,郝春荣. 介入治疗对肝细胞癌层粘连蛋白表达的影响[J]. 影像诊断与介入放射学, 2001, 10(2): 91-94 |
| 作者姓名： | 肖恩华 胡国栋 刘鹏程 胡道予 刘绍春 郝春荣 |
| 作者单位： | 1. 510060,中山医科大学肿瘤防治中心肝胆科 2. 华中科技大学同济医学院附属同济医院放射科 3. 深圳市中心医院放射科 4. 华中科技大学同济医学院病理免疫室 |
| 基金项目： | 国家"九五"攻关项目(96-907-03-01) |
| 摘 要： | 目的：研究介入治疗对肝细胞癌（HCC）层粘连蛋白（LN）表达的影响。方法：手术病理证实的HCC98例,单纯手术组57例,介入治疗后Ⅱ期切除（介入治疗组）41例,采用免疫化方法检测各标本LN。结果：LN表达阳性率和表达强度,介入治疗组较单纯手术组显著降低。结论：介入治疗可拮抗LN的作用而抑制 HCC浸润转移潜能。 |
| 关 键 词： | 肝细胞癌 介入治疗 免疫组织化学 |
| 修稿时间： | 2000-05-14 |
The effect of interventional treatment on laminin expression of hepatocellular carcinoma |
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| XIAO Enhua,HU Guodong,LIU Pengcheng,et al.. The effect of interventional treatment on laminin expression of hepatocellular carcinoma[J]. Journal of Diagnostic Imaging & Interventional Radiology, 2001, 10(2): 91-94 | |
| Authors: | XIAO Enhua HU Guodong LIU Pengcheng et al. |
| Affiliation: | XIAO Enhua,HU Guodong,LIU Pengcheng,et al. Hepatobiliary Department,Cancer Center,Sun Yat - sen University of Medical Sciences,GuangZhou. 510060 |
| Abstract: | To study the effect of interventional treatment on laminin(LN) expression of hepatoeel-lular carcinoma (HCC), Methods 98 patients with histologically - proven HCC were divided into 2 groups: 57 patients without previous treatment (only surgery group) and 41 patients undergoing interventional treatment before operation (interventional group) . LN was measured by immunohistochemistry. Results The percentages of LN positive cases and the degree of In expression were significantly higher and stronger in patients in only sutgery group than in those in interventional group. Conclusions Interventional treatment could significantly inhibit the expression of LN and might restrict the invasiveness and/or metastasis of HCC. |
| Keywords: | Carcinoma Hepatocellular Interventional treatment Immunohistochemistry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |