脾康灵胶囊质量标准研究

目的建立脾康灵的质量标准。方法采用薄层色谱法对陈皮、肉桂进行定性鉴别；采用高效液相色谱法对肉桂的挂皮醛进行含量测定。色谱柱为Diamonsil C18（250mm×4．6mm，5μm）。流动相为乙腈．水溶液（35：65）。检测波长为290nm。结果薄层色谱能检出陈皮、肉挂；桂皮醛线性关系良好（r=0.9998），平均回收率为98．27％，RSD=1．81％。结论陈皮、肉桂鉴别方法简便、快速，重现性好；高效液相色谱法测定桂皮醛含量准确、快速。

Study on quality Standards for Pi kang-ling capsules

OBJECTIVE To study and establish the quality standards for Pi kang-ling capsules. METHODS TLC method was used to identify the drugs of Tangerine Peel and Cortex Cinnamomi. HPLC method was used to determinate the contents of Trans-Cinnamaldehyde. The HPLC condition of Trans-Cinnamaldehyde was as fol- lows： column was Diamonsil Cl8 （250mm × 4.6mm, 5μm）, the mobile phase consisted of acetonitrile-water（35： 65）, the UV detection wavelength was at 290nm. RESULTS The Tangerine Peel and Cortex Cinnamomi can be identified by TLC method;The calibration curve of Trans-Cinnamaldehyde was linear （r = 0.9998）. The average recovery was 98.27 96 with RSD of 1.81%. CONCLUSION The TLC method is exclusive, reprodueibl and suitable for the identity of Tangerine Peel and Cortex Cinnamomi. The HPLC method is exclusive, quickly and quality suitable.