| Bestrophin氯通道的研究进展 |
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| 引用本文： | 王觅,关永源.Bestrophin氯通道的研究进展[J].中国药理学通报,2009,25(2). |
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| 作者姓名： | 王觅 关永源 |
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| 作者单位： | 中山大学中山医学院药理学教研室,广东,广州,510080 |
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| 摘 要： | Bestrophin是最新发现的一类Cl-通道,其同源序列广泛存在于动物、真菌、原核生物。Bestrophin受到Ca2+、细胞容积和自身结构的调节。在嗅觉传导、视网膜色素上皮细胞液体的转运以及细胞的增殖中发挥了重要作用。
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| 关 键 词： | bestrophin Cl~-通道 卵黄样黄斑变性 |
Growing insights into bestrophin |
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| WANG Mi,GUAN Yong-yuan.Growing insights into bestrophin[J].Chinese Pharmacological Bulletin,2009,25(2). |
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| Authors: | WANG Mi GUAN Yong-yuan |
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| Abstract: | Bestrophins have recently been proposed to comprise a new family of chloride channels.Homologous sequences have been found in animals,fungi and prokaryotes.Bestrophins are regulated by Ca2+,cell volume as well as auto-inhibitory domain and play important roles in olfactory transduction,fluid transport and cell proliferation. |
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| Keywords: | bestrophin |
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