| 益气活血降浊法防治慢性肾衰竭的实验研究 |
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| 引用本文： | 于尔康,高继宁,李宜放,庞晓英. 益气活血降浊法防治慢性肾衰竭的实验研究[J]. 中国中西医结合肾病杂志, 2001, 2(12): 702-704 |
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| 作者姓名： | 于尔康 高继宁 李宜放 庞晓英 |
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| 作者单位： | 1. 山西省中医药研究院肾病研究所,太原,030012
2. 山西中医学院,太原,030024 |
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| 摘 要： | 目的：观察“肾毒灵”对慢性肾衰竭大鼠模型的保护作用,并探讨其疗效机制。方法：根据益气活血降浊法,制成“肾毒灵”胶囊,用0．75％腺嘌呤饲料喂养大鼠制成肾衰竭模型,灌胃观察“肾毒灵”胶囊的疗效。喂养50d后测血清中BUN、Scr、钙、磷、白蛋白和血色素的水平,并取肾组织做病理检查。结果：与对照组比较,“肾毒灵”胶囊可明显降低血清中BUN和Scr的含量,预防性拮抗钙磷失调;改善贫血和提高血浆蛋白的水平,同时减轻了肾组织的病理损害。结论：肾毒灵方具有促进氮质排泄,改善尿毒症合并症,减轻肾间质炎症,促进受损组织恢复的功能。
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| 关 键 词： | 慢性肾衰竭 肾毒灵 病理 益气活血降浊法 中草药治疗 |
| 修稿时间： | 2000-07-28 |
An Experimental Study of Prevention and Treatment on Chronic Renal Failure with Yi Qi Huo Xue Jiang Zhuo Fa |
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| YU Erkang,GAO Jining,LI Yifang,et al. An Experimental Study of Prevention and Treatment on Chronic Renal Failure with Yi Qi Huo Xue Jiang Zhuo Fa[J]. Chinese Journal of Integrated Traditional and Western Nephrology, 2001, 2(12): 702-704 |
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| Authors: | YU Erkang GAO Jining LI Yifang et al |
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| Abstract: | Objective:The capsule "Shen-du-ling"is made up of the drugs for supplementing qi,activating blood circulation and drainaging turbid materials from the body.Methods:the effect of which was observed on rat models of chronic renal failure induced by eating 0.75% adenine contained food.After the treatment of Shen-du-ling for 50 days,the level of blood urea nitrogen and serum creatinine was lower in the treated groups than those in the controls.Results:The drugs also increased the level of serum calcium and decreased the serum phosphorus in the treated groups.Conclusion:The light microscopy revealed that Shen-du-ling alleviated the pathological changes in the treated groups. |
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| Keywords: | Chronic renal failure Shen Duling Biochemistry Pathology |
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