| 柞蚕抗菌肽对人鼻咽癌细胞CNE 2骨架的作用 |
| |
| 引用本文： | 凌斌勋,孟庆龄,王建宁,鲍伟宏,吴娟. 柞蚕抗菌肽对人鼻咽癌细胞CNE 2骨架的作用[J]. 南京军医学院学报, 2003, 25(1): 1-3 |
| |
| 作者姓名： | 凌斌勋 孟庆龄 王建宁 鲍伟宏 吴娟 |
| |
| 作者单位： | 1. 解放军第414医院血液科,江苏,南京,210015
2. 镇江市江滨医院骨科,江苏,镇江,212000 |
| |
| 摘 要： | 目的：探讨柞蚕抗菌肽对癌细胞骨架的破坏作用。方法：用柞蚕抗菌肽对人鼻咽癌细胞CNE2处理12和18h，抗微管蛋白单克隆抗体检测细胞骨架结构的变化。结果：免疫组织化学染色见抗菌肽处理后细胞骨架分布不均匀，形态不规则，散乱，卷缩。结论：柞蚕抗菌肽具有较明显的破坏人鼻咽癌细胞株CNE2细胞骨架的作用。
|
| 关 键 词： | 柞蚕抗菌肽 细胞骨架 鼻咽癌 CNE2骨架 |
| 文章编号： | 1009-1874(2003)01-0001-03 |
| 修稿时间： | 2002-11-01 |
Effect of cecropin on cytoskeleton of human nasopharyngeal carcinoma cell line CNE 2 |
| |
| LING Bin xun ,MENG Qing ling ,WANG Jian ning ,BAO Wei hong ,WU Juan. Effect of cecropin on cytoskeleton of human nasopharyngeal carcinoma cell line CNE 2[J]. Journal of Nanjing Military Medical College, 2003, 25(1): 1-3 |
| |
| Authors: | LING Bin xun MENG Qing ling WANG Jian ning BAO Wei hong WU Juan |
| |
| Affiliation: | LING Bin xun 1,MENG Qing ling 2,WANG Jian ning 1,BAO Wei hong 1,WU Juan 1 |
| |
| Abstract: | Objective: To explore the destructive effect of cecropin on cytoskeleton of human nasopharyngeal carcinoma cell line CNE 2. Methods: CNE 2 cells of human nasopharyngeal carcinoma were treated by cecropin for 12 and 18 hours, and the changes of cytoskeleton were detected by anti tubulin monoclonal antibody. Results: Cytoskeletons distributed unevenly, their morphology was irregular, dishevelled and shrunk after being treated with immunohistochemistry staining. Conclusion: Cecropin has more significant destructive effects on cytoskeleton of human nasopharyngeal carcinoma cell line CNE 2. |
| |
| Keywords: | cecropin cytoskeleton nasopharyngeal carcinoma |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
