Electrospun fibers and their application in drug controlled release,biological dressings,tissue repair,and enzyme immobilization |
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| Authors: | Yue Sun Shihong Cheng Wenjuan Lu Yanfeng Wang Pingping Zhang Qingqiang Yao |
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| Institution: | School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan 250062 Shandong China ; Institute of Materia Medica, Shandong Academy of Medical Sciences, Key Laboratory for Biotech-Drugs Ministry of Health, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Jinan 250062 Shandong China, Fax: +86-0531-82919706, +86-0531-82919706 |
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| Abstract: | Electrospinning is a method of preparing microfibers or nanofibers by using an electrostatic force to stretch the electrospinning fluid. Electrospinning has gained considerable attention in many fields due to its ability to produce continuous fibers from a variety of polymers and composites in a simple way. Electrospun nanofibers have many merits such as diverse chemical composition, easily adjustable structure, adjustable diameter, high surface area, high porosity, and good pore connectivity, which give them broad application prospects in the biomedical field. This review systematically introduced the factors influencing electrospinning, the types of electrospun fibers, the types of electrospinning, and the detailed applications of electrospun fibers in controlled drug release, biological dressings, tissue repair and enzyme immobilization fields. The latest progress of using electrospun fibers in these fields was summarized, and the main challenges to be solved in electrospinning technology were put forward.Electrospun fibers have gained considerable attention in drug controlled release, biological dressings, tissue repair and enzyme immobilization fields. |
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