Repair of dentine-related lesions without a drill or injection |
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| Authors: | Yu Yuan Zhang Hai Ming Wong Colman P. J. McGrath Quan Li Li |
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| Affiliation: | Faculty of Dentistry, The University of Hong Kong, The Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong, Fax: +852 25593803, +852 28590261 ; Department of Prosthodontic, College and Hospital of Stomatology, Anhui Medical University, No. 69, Meishan Road, Hefei China, Fax: +86 0551 5111538, +86 0551 5118677 |
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| Abstract: | For covering the shortages of traditional treatments, a novel and non-invasive system was developed with the simple adaption of nature''s own repair process, while an extrinsic electric field was introduced to improve its remineralization kinetics. In an in vivo study, acid-etched rabbit dentine was used to evaluate the remineralization efficacy and safety of the system. The exposed dentine tubules were fully occluded after 5 hours/1.0 mA and 8 hours/0.5 mA of remineralization. After 5 hours of remineralization (1.0 mA), the micro-hardness of the demineralized dentine was fully recovered, equal to native rabbit dentine. Haematoxylin–eosin staining demonstrated no obvious inflammatory reaction. This study provides a feasible solution to realize rapid repair of dentine.For covering the shortages of traditional treatments, a novel and non-invasive system was developed with the simple adaption of nature''s own repair process, while an extrinsic electric field was introduced to improve its remineralization kinetics. |
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