A ratiometric and colorimetric probe for detecting Hg2+ based on naphthalimide–rhodamine and its staining function in cell imaging |
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| Authors: | Yuesong Wang Haichang Ding Shuai Wang Congbin Fan Yayi Tu Gang Liu Shouzhi Pu |
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| Institution: | Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang Jiangxi 330013 PR China, Fax: +86-791-83831996, +86-791-83831996 |
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| Abstract: | In this work, a rhodamine derivative was developed as a colorimetric and ratiometric fluorescent probe for Hg2+. It exhibited a highly sensitive fluorescence response toward Hg2+. Importantly, studies revealed that the probe could be used for ratiometric detection of Hg2+, with a low detection limit of 0.679 μM. The mechanism of Hg2+ detection using compound 1 was confirmed by ESI-MS, 1H NMR, and HPLC. Upon the addition of Hg2+, the rhodamine receptor was induced to be in the ring-opening form via an Hg2+-promoted hydrolysis of rhodamine hydrazide to rhodamine acid. In addition to Hg2+ detection, the naphthalimide–rhodamine compound was proven to be effective in cell imaging.A new probe based on naphthalimide–rhodamine was applied in recognition of Hg2+ by a FRET mechanism. |
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