高压氧对人重度牙周炎的作用及疗效维持时间

目的探讨高压氧(HBO)对人重度牙周炎的作用及疗效维持时间。方法30例牙周炎患者随机分为治疗组和对照组2组,治疗组用HBO治疗,对照组用漱口液含漱。常规测定2组在治疗前、后和治疗1年后的GI、SBI、PD、AL、PLI和龈沟液量(GCF),用激光多普勒血流仪测定牙龈血流量(GBF)。结果HBO治疗后GI降低1.1,SBI降低1.2,PD和AL均减少0.7mm,PLI减少0.8,GCF量降低2.0;GBF增加1.8倍。与对照组比较,均有显著性差异(P<0.01)。HBO治疗1年后的各牙周指标与治疗结束时比较,GI和SBI均轻度增加,而PD、AL、PLI、GCF和GBF无明显改变(P>0.05)。结论HBO对人重度牙周炎有较好治疗效果,其疗效可维持1年以上。

Effects and Holding time of Hyperbaric Oxygen on Human Severe Periodontitis

Objective This paper studied the therapeutic effects and holding time of hyperbaric oxygen(HBO)on hu-man severe periodontitis.Methods30cases with periodontitis were selected and randomly divided into2groups,i.e.the HBO group and control group.For HBO group,they were exposed to a pressure of0.25MPa.For control group,they were rinsed with gargle.Gingival indices(GI),sulcus bleeding indices(SBI),plaque index(PLI),probing depth(PD),attachment loss(AL)and gingival crevicular fluid(GCF)were measured during both the first and last clinical visits,and1year after HBO therapy.The gingival blood flow(GBF)were measured by Laser Doppler Flowmeter.Results HBO can decrease GI of patients with periodontitis by1.1decrease SBI by1.2,lower PD and AL by0.7mm,decrease the volume of GCF by2.0,and significant differences could be seen in the above indices between pre and post HBO therapy.The GBF had a1.8folds increase after HBO exposure.GI and SBI one year after HBO therapy were larger than that of the time after HBO therapy.There were no significant differences in the PLI,PD,AL,GCF,GBF between post HBO therapy and1year after HBO thera-py.Conclusion HBO had good therapeutic effects on human severe periodontitis,the effects can keep more than1year.