| 以结膜巨噬细胞作为抗原呈递细胞诱导实验性过敏性结膜炎 |
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| 引用本文： | 周萍萍,刘远光,王冬兰,福岛敦树.以结膜巨噬细胞作为抗原呈递细胞诱导实验性过敏性结膜炎[J].黑龙江医药科学,2011,34(2):8-9. |
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| 作者姓名： | 周萍萍 刘远光 王冬兰 福岛敦树 |
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| 作者单位： | 1. 佳木斯大学附属第一医院眼科,黑龙江,佳木斯,154003
2. 高知大学医学部眼科,日本南国市,783-8505 |
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| 摘 要： | 目的:过敏性结膜炎(AC)是发生在眼部的超敏反应,然而抗原呈递细胞(APCs)参与实验性过敏性结膜炎的发展过程,APCs接受,加工处理抗原并呈递给T细胞,探讨和研究此抗原呈递细胞的类型.方法:对特异性卵清蛋白(OVA)T细胞受体 转基因老鼠(DO11.10)进行处理,对两组实验鼠分别进行结膜下注射磷酸盐缓冲液(PBS)...
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| 关 键 词： | 过敏性结膜炎 嗜酸性粒细胞 抗原呈递细胞 巨噬细胞 |
Conjunctival macrophages act as antigen-presenting cells in development of experimental allergic conjunctivitis |
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| ZHOU Ping-ping,LIU Yuan-guang,WANG Dong-lan,Fukushima A.Conjunctival macrophages act as antigen-presenting cells in development of experimental allergic conjunctivitis[J].Heilongjiang Medicine and Pharmacy,2011,34(2):8-9. |
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| Authors: | ZHOU Ping-ping LIU Yuan-guang WANG Dong-lan Fukushima A |
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| Institution: | ZHOU Ping-ping1,LIU Yuan-guang1,WANG Dong-lan1,Fukushima A2(1.Department of Ophthalmology,the First Affiliated Hospital of Jiamusi University,Jiamusi 154003,China,2.Department of Ophthalmology,Kochi Medical School,Nankoku-city,Japan 783-8505) |
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| Abstract: | Objective:To investigate and analyze the type of antigen(Ag)-presenting cells(APCs).Methods:Ovalbumin(OVA)-specific T cell receptor transgenic(DO11.10) mice were divided into two groups.DO11.10 mice were subconjunctivally injected with PBS,OVA-gold.24h later,the conjunctival tissue was harvested for immunohistochemistry analysis and light microscopy to identify cells that engulfed OVA-gold.Results:Subconjunctival injection of OVA-gold induced infiltration of eosinophils and CD4-positive T cells into the con... |
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| Keywords: | allergic conjunctivitis eosinophils APCs macrophages |
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