焦点解决短期疗法合用帕罗西汀治疗强迫症的对照研究

目的:评价焦点解决短期疗法(SFBT)合用帕罗西汀治疗强迫症的临床疗效。方法:将符合CCMD-3诊断标准的60例强迫症患者随机分为实验组(SFBT合用帕罗西汀)和对照组(单用帕罗西汀),疗程为10周。用耶鲁-布朗强迫量表(Y-BOCS)分别于治疗后第2、4、6、8、10周末评定两组的临床疗效。结果:两组在治疗2、4、6、8、10周后Y-BOCS评分均有显著降低(P<0.05或P<0.01),且实验组明显低于对照组(P<0.05或P<0.01)。结论:SFBT合用帕罗西汀和单用帕罗西汀治疗强迫症均有显著疗效,且前者疗效优于后者。

Comparative Study of Solution-Focused Brief Therapy (SFBT) Combined with Paroxetine in the Treatment of Obsessive-Compulsive Disorder

bjectives:To evaluate the effect of So1ution-Focused Brief Therapy(SFBT) combined with paroxetine in the treatment of Obsessive-Compulsive Disorder(OCD). Methods:60 outpatients who met CCMD-3 criteria for OCD were randomly divided into experiment group (SFBT plus Paroxetine,n=30)and control group (paroxetine only,n=30) and treated for 10 weeks. The efficacy was assessed with Yale-Brown 0bsessive- Compulsive Rating Scale (Y-BOCS) at the end of week 2,4,6,8,and 10. Results:The Y-BOCS score in two groups were significantly decreased 2,4,6,8,and 10 weeks after treatment (P<0.05 or P<0.01),and the Y-BOCS score in experiment group was significantly lower than that in control group (P<0.05 or P<0.01). Conclusions: SFBT combined with paroxetine and paroxetine have significant efficacy in the treatment of OCD,and SFBT combined with paroxetine has better effect than paroxetine alone.