膀胱嗜铬细胞瘤8例报告

目的提高膀胱嗜铬细胞瘤的诊断和治疗水平。方法回顾性分析本院8例膀胱嗜铬细胞瘤的临床资料,8例膀胱嗜铬细胞瘤患者均通过膀胱镜检查获得定位诊断并均经手术治疗,其中7例行膀胱部分切除,1例行全膀胱切除术。结果8例患者术后病理诊断均为膀胱嗜铬细胞瘤,8例获随访,时间5个月～3年,6例痊愈,术后血压均恢复正常,临床症状消失,1例于术后8个月死于脑出血,1例术后2年复发,再次手术。结论血尿、排尿时头晕、头痛、心慌及血压升高为膀胱嗜铬细胞瘤的主要症状,尿香草扁桃酸测定是主要的定性检查手段,膀胱镜是最主要的定位检查手段,手术切除是首选治疗方法,术前准备同其他部位嗜铬细胞瘤,极为重要,术式选择应依据病灶大小及部位。

DIAGNOSIS AND TREATMENT OF PHEOCHROMOCYTOMA OF THE BLADDER

Objective To improve the diagnosis and treatment of pheochromocytoma of the bladder. Methods Clinical data of 8 cases of pheochromocytoma in bladder were analyzed retrospectively. Cystoscope has confirmed the diagnosis and the site of localization of pheochromocytoma in all cases. 7 had performed partial cysteetomy and 1 had performed total cystectomy. Results All the 8 cases were pathologically diagnosed as pheechremocytoma in bladder,8 cases had been followed up from 5 months to 3 years. The blood pressure restored to normal successfully after operation and the clinical symptoms disappeared in 6 eases. 1 case was died in cerebral hemorrhage on follow - up 8 months. 1 case was surgically treated due to recurrence 2 years after initial operation. Conclusion Flustration,headache and dizzy during urination, hematuria, and hypertension were the main clinical symptoms of pheochromocytoma in bladder. Urinary VMA （ Vanillyl mandelic acid ） is the main way of quantitative diagnosis, Cystoscopy is the main method for the localization of disease, Surgical operation is still the firstly selected mean to treat phecchromocytoma in bladder. And treatment of this lesion requires the same preparation as for any other site of pheochromocytoma and choice of correct operation methods was determined by the site and size of phcochromocytoma in bladder.