| Survivin、Cox-2在结肠腺瘤性息肉及腺癌中的表达 |
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| 引用本文： | 郑荣娟,司雁菱,张志勇,姜丽,吴瑜. Survivin、Cox-2在结肠腺瘤性息肉及腺癌中的表达[J]. 华北煤炭医学院学报, 2010, 12(1): 9-10 |
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| 作者姓名： | 郑荣娟 司雁菱 张志勇 姜丽 吴瑜 |
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| 作者单位： | 1. 河北省唐山工人医院消化科,河北唐山,063000
2. 河北省唐山工人医院病理科,河北唐山,063000 |
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| 摘 要： | ①目的探讨非家族性大肠腺瘤性息肉及腺癌中生存素（Survivin）及环氧化酶2（Cox-2）的表达。②方法收集我院2006年1月~2007年12月大肠腺瘤性息肉及腺癌标本,利用免疫组化技术分别检测40例腺瘤性息肉,40例大肠腺癌及相应的正常黏膜对照中Sur-vivin、Cox-2的表达情况。③结果Survivin及Cox-2在正常黏膜与腺瘤性息肉及腺癌中的表达依次增强,且均有统计学意义（P〈0.01）。④结论Survivin、Cox-2可能是大肠腺瘤发展及癌变过程中的重要促进因子,对于预测大肠腺瘤癌变可能性及化学干预有重要意义。
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| 关 键 词： | 腺瘤性息肉 大肠癌 Survivin Cox-2 |
Expression of survivin and Cox-2 in colonic adenomatous polyp and colon cancer |
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| ZHENG Rongjuan,SI Yanling,ZHANG Zhiyong,et al. Expression of survivin and Cox-2 in colonic adenomatous polyp and colon cancer[J]. Journal of North China Coal Medical College, 2010, 12(1): 9-10 |
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| Authors: | ZHENG Rongjuan SI Yanling ZHANG Zhiyong et al |
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| Affiliation: | Department of Gastroenterology/a>;Tangshan Worker Hospital/a>;Tangshan 063000/a>;China |
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| Abstract: | Objective To detect the expression of Survivin and Cox-2 in colonic adenomatous polyp and colon cancer.Methods The samples of colonic adenomatous polyp and colon cancer were collected from Jan 2006 to Dec 2007,and the expressions of Survivin protein and Cox-2 protein in 40 colonic adenomatous polyp,40 colon cancer and normal mucous membrane were examined with immunohistochemical staining.Results The expressions of Survivin and Cox-2 in normal mucous membrane,colonic adenomatous polyp and colon cancer were s... |
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| Keywords: | Colonic adenomatous polyp.Colon cancer.Survivin.Cox-2 |
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