奥美拉唑联合呋喃唑酮及阿莫西林治疗十二指肠溃疡疗效观察

目的 观察奥美拉唑联合呋喃唑酮及阿莫西林治疗十二指肠溃疡的疗效.方法 将十二指肠溃疡患者50例随机分为两组:治疗组26例,予以奥美拉唑每日清晨空腹口服20 mg,治疗4周,呋喃唑酮100 mg,3次/d,阿莫西林1000 mg,2次/d,治疗2周,治疗期间不加其他药物.对照组:奥美拉唑每日清晨空腹口服20 mg,治疗4周.结果 治疗组:治愈率53.85%,好转率42.31%,有效率98.16%;对照组:治愈率41.67%,好转率37.50%,有效率79.17%.治疗组和对照组总有效率经统计学处理有显著差异(P＜0.05).结论 奥美拉唑联合呋喃唑酮及阿莫西林治疗十二指肠溃疡能改善临床症状和促进溃疡愈合.

Omeprazole, furazolidone and amoxicilin for duodenal ulcer

Objective To investigate the efficacy of omeprazole combined with furazolidone and amoxicilin in the treatment of duodenal ulcer.Methods 50 patients with duodenal ulcer were randomly assigned in a 1:1 ratio to receive oral omeprazole 20mg daily before breakfast for 4 weeks,as well as furazolidone 100 mg three times daily and amoxicilin 1000mg twice daily for 2 weeks or to receive oral omeprazole 20mg daily for 4 weeks(control group).Results The combination treatment group had a cure rate of 53.84% and an improvement rate of 42.31%,with overall effectiveness rate being 98.16%;The control group had a cure rate of 41.67% and an improvement rate of 37.50%,with overall effectiveness rate being 79.17%.The differences between the two groups were statistically significant(P<0.05).Conclusion Omeprazole in conjunction with furazolidone and amoxicilin is effective and safe for duodenal ulcer,it can relieve symptoms and promote the healing of ulcer.