| Abstract: | We performed simultaneous fasting and fedantroduodenal manometry and EGG in 25 children withfunctional bowel disorders. Three patients (12%) had anuninterpretable EGG. The manometric studies showedsevere neuropathy in six patients; milder neuropathicchanges in five patients; postprandial hypomotility inone patient; myopathy in four patients, and normalmotility in the remaining six patients. The percentage of tachygastria time (frequency >3.5cycles/min) was higher in the patients with mild (44.1± 15.8%) and severe (48 ± 19.1%)neuropathy than in the patients with myopathy (20± 16.2%, P < 0.05) or with normal motility (23 ± 13.3%, P< 0.05). There was a considerable overlap in thepercentage of tachygastria and total arrhythmia timeamong the different study groups. The ratio of post- to preprandial power was significantly higher (2.5± 0.07) in children with normal motility than inthe other patients groups. Every child with totalarrhythmia time <35% and a ratio of post-topreprandial power >2.4 had normal manometry. In summary,EGG differentiated groups of children with normalmanometry from others with neuropathic or myopathicchanges, but in a minority of patients the study was not interpretable and there was overlap in EGGresults between children with normal and abnormalmanometry. |
