髁状突或髁状突软骨缺损对生长期大鼠下颌骨生长发育的影响

目的:观察髁状突切除术和髁状突软骨全层削刨术对生长期大鼠下颌骨发育的影响,为临床治疗儿童发育期髁状突病变提供理论指导。方法:36只大鼠平均分为3组,髁状突切除组、髁状突软骨全层削刨组和正常对照组,分别于术后6、12周处死后测量下颌骨大体标本并做髁状突中份软骨组织学观察。结果:同正常对照组比较,术后6、12周髁状突切除组下颌升枝高度(H)、下颌体高度(M)、下颌体长度(L)都明显缩短;两手术组间H和L差异显著(P<0.01);两手术组的修复组织大部分为纤维软骨样组织。结论:下颌骨的生长发育是内部生长中心发育和外部功能刺激双重作用的结果。

Mandibular growth after condylectomy or defect of condyle cartilage in growing rats

Objective:To observe the development and growth of the mandibular in growing rats after condylectomy or defect of condyle cartilage.Methods:Thirty-six rats were randomly divided into three groups.The first group were condylectomized on the neck.In the second group,the full cartilage on the anterior slope was exercised and the third was control group.Results:Compared with the controls,the height of the ramus(H),the height of mandible(M)and the length of mandible(L)in first group were signifi-cantly shortened6and12weeks after operation.The difference between the first and second groups was significant except the height of mandible(M).Conclusion:The growth and development of mandible was the result of cartilage growth and the stimulus of functional matrix.