| 缺血性中风红细胞膜脂质过氧化物与膜粘度关系的研究 |
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| 引用本文： | 冷贵生,郭述苏,王忠兰,于金萍. 缺血性中风红细胞膜脂质过氧化物与膜粘度关系的研究[J]. 中国血液流变学杂志, 1994, 0(2) |
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| 作者姓名： | 冷贵生 郭述苏 王忠兰 于金萍 |
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| 作者单位： | 济南军区总医院!山东济南250031 |
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| 摘 要： | 本文通过对脑梗塞患者及健康对照者进行红细胞膜脂质过氧化物、膜微粘度及红细胞变形能力的测定，发现患者组红细胞膜脂质过氧化物、膜微粘度显并高于对照组，红细胞变形能力显著低于对照组，且患者组红细胞膜脂质过氧化物含量与后两者有直线相关关系，提示对中风患者进行抗脂质过氧化治疗可能具有一定意义。
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| 关 键 词： | 微粘度 脂质过氧化物 脑梗塞 |
CORRELATION BETWEEN MICROVISCOSITY OF ERYTHROCYTE MEMBRANE AND MALONYLDIALDEHYDE OF ERYTHROCYTE IN ISCHEMIC STROKE |
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| Guisheng Leng Shusu Ge Zhonglan Wang Jingping Yu. CORRELATION BETWEEN MICROVISCOSITY OF ERYTHROCYTE MEMBRANE AND MALONYLDIALDEHYDE OF ERYTHROCYTE IN ISCHEMIC STROKE[J]. Chinese Journal of Hemorheology, 1994, 0(2) |
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| Authors: | Guisheng Leng Shusu Ge Zhonglan Wang Jingping Yu |
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| Affiliation: | Guisheng Leng Shusu Ge Zhonglan Wang Jingping Yu Department of Neuology,Jinan General Military Hospital Jinan 250031 |
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| Abstract: | The microviscosity and malonyldialdehyde (MDA) level of erythrocyte membrane from 62 ischemic stroke patients and 34 control subjects were measured. The MDA level and microviscosity of erythrocyte membrane of patients significantly increased, but erythrocyte deformability decreased , when compared with the control subjects. In addition, the MDA level of erythrocyte membrane in ischemic patients inversely correlated with microviscosity and deformability. These findings suggested that decreasing membrane lipid peroidation may be important for treating strokes. |
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| Keywords: | microviscositymalonyldialdehyde (MDA)cerebral infarction |
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