生长抑素联合空肠营养管在新生儿先天性肠闭锁术后的应用效果观察

目的观察生长抑素联合空肠营养管在新生儿先天性肠闭锁术后的应用效果。方法选择行先天性肠闭锁术新生儿50例,根据不同术后营养治疗方法分为对照组和观察组,每组25例。对照组给予单一生长抑素治疗,观察组给予生长抑素联合空肠营养管治疗,对比两组患儿的手术方式、术后住院时间、体质量变化、不良反应发生情况等。结果两组患者的手术方式比较无明显统计学差异(P0.05);与对照组比较,观察组患者的住院时间明显缩短,3、7、14d的体质量明显增长,差异具有统计学意义(P0.05)。观察组不良反应发生率4.0%(1/25)明显低于对照组32.0%(8/25)(P0.05)。观察组隐血试验转阴时间、血红蛋白下降等情况都显著优于对照组(P0.05)。结论生长抑素联合空肠营养管应用于新生儿先天性肠闭锁术后患儿中,能够改善患儿的营养状态,降低不良反应发生率,具有较高的应用价值。

The research on effect of somatostatin combined with jejunal nutrition tube on neonatal congenital intestinal atresia

［Abstract］ Objective To observe the effect of somatostatin combined with jejunal nutrition tube onneonatal congenital intestinal atresia. Methods Fifty neonates with congenital intestinal atresia were divided into control group and observation group by different treatment method. The control group was treated with single somatostatin，the observation group was treated with somatostatin combined with jejunal nutrition tube，and the changes of body mass and adverse reactions were compared between the two groups. Results There was no significant difference in surgical methods between the two groups （P> 0.05）. Compared with the control group，the length of hospitalization in the observation group was significantly shorter than that in the control group（P<0.05）. After 3，7 and 14 days of treatment，the increase of body mass in the observation group was significantly greater than that in the control group（P< 0.05）. The incidence of adverse reactions was 4.0%（1/25）in the observation group and 32.0%（8/25）in the control group（P<0.05）. The occult blood test of the observation group was significantly better than that of the control group （P<0.05）. Conclusion Somatostatin combined jejunum nutrition tube used in postoperative children with neonatal congenital intestinal atresia，it can improve the nutritional status of children，reduce the incidence of adverse reactions，has higher application value.