PET-CT乏氧显像及其在肺癌中的研究进展

PET-CT乏氧显像可以在功能和形态上对活体肿瘤乏氧区进行高分辨率的勾画,从而可以对肿瘤的乏氧状况进行定量分析、及时监测。综述了PET-CT乏氧显像对肺癌的生物学评价、治疗方案选择、治疗效果监测及预后预测等方面的应用及存在的问题。

Advances of research on PET-CT hypoxia imaging in lung cancer

PET-CT, as a single imaging modality for whole body providing both anatomic and biological information, offer the possibility of in vivo mapping of regional tumor hypoxia with adequate anatomical resolution as well as monitoring therapy through follow-up mapping of hypoxia. Some new advances of research and clinical study on PET-CT hypoxia imaging in lung cancer were summarized briefly, including tracers, the detections of hypoxia, therapy planning, predictioas and outcome.