| 天年饮调节血脂及抗氧化作用的实验研究 |
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| 引用本文： | 陈志宏,宋成军,高福禄. 天年饮调节血脂及抗氧化作用的实验研究[J]. 时珍国医国药, 2006, 17(4): 528-529 |
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| 作者姓名： | 陈志宏 宋成军 高福禄 |
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| 作者单位： | 承德医学院中心实验室,河北,承德,067000 |
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| 基金项目： | 河北省科技厅资助项目(No.03547003D) |
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| 摘 要： | 目的观察天年饮(Tiann ianyin,TNY)对衰老大鼠血脂的影响及TNY的抗氧化作用。方法选用成年雄性SD大鼠40只,随机分为4组:正常组、衰老模型组、TNY用药组及阴性对照组,每组均为10只。D-半乳糖连续腹腔注射制作亚急性衰老的大鼠模型,检测TNY灌胃前后血清总胆固醇(TC)、甘油三酯(TG)和高密度脂蛋白(HDL-C)的含量及超氧化物歧化酶(SOD)的活性。结果模型组大鼠血清TC、TG含量升高、HDL-C含量和SOD的活性下降P<0.05或P<0.01。TNY可以降低模型大鼠TC、TG的含量(TNY组与模型组相比P<0.01,P<0.05)及提高HDL-C的含量和SOD的活性(TNY组与模型组相比P<0.05)。结论TNY具有明显的调节血脂及抗氧化作用,可延缓机体衰老。
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| 关 键 词： | 天年饮 亚急性衰老 血脂 超氧化物岐化酶 |
| 文章编号： | 1008-0805（2006）04-0528-01 |
| 收稿时间： | 2005-07-11 |
| 修稿时间： | 2006-01-25 |
Study on the Effect of TNY on Blood-lipid Regulation and Antioxidation |
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| CHEN Zhi-hong,SONG Cheng-jun,GAO Fu-lu. Study on the Effect of TNY on Blood-lipid Regulation and Antioxidation[J]. Lishizhen Medicine and Materia Medica Research, 2006, 17(4): 528-529 |
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| Authors: | CHEN Zhi-hong SONG Cheng-jun GAO Fu-lu |
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| Affiliation: | The Central Laboratory of Chengde Medical College, Chengde, Hebei 067000, China |
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| Abstract: | ObjectiveTo study the effect of Tiannianyin(TNY) on blood-lipid regulation and antioxidation.Methods40 adult male SD rats were used in this study and divided into 4 groups at random: normal group,aging model group,TNY treatment group and negative control group,each group had 10 rats.The sub-acute aging model rats were made by injecting D-gal into the rats' abdominal cavity continually.Then the value of TC,TG,HDL-C and SOD in serum were detected before and after taking TNY.ResultsTNY could significantly reduce the value of TC,TG(compare with model rats: P<0.01,P<0.05) and increase the value of HDL-C,SOD(compare with model rats: P<0.05)in serum.ConclusionTNY has obvious effects on blood-lipid regulation and antioxidation,TNY has fairly anti-aging effect. |
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| Keywords: | Tiannianyin Sub-acute aging Blood-lipid Superoxide dismutase |
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