Cambios en el estadio y presentación clínica del cáncer de pulmón a lo largo de dos décadas |
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Authors: | Virginia Leiro-Ferná ndez,Cecilia Mouronte-Roibá s,Cristina Ramos-Herná ndez,Maribel Botana-Rial,Ana Gonzá lez-Piñ eiro,Esmeralda Garcí a-Rodrí guez,Cristina Represas-Represas,Alberto Ferná ndez-Villar |
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Affiliation: | 1. Servicio de Neumología, Complexo Hospitalario Universitario de Vigo (CHUVI), Instituto de Investigación Biomédica de Vigo (IBIV), Vigo, España;2. Servicio de Anatomía Patológica, Complexo Hospitalario Universitario de Vigo (CHUVI), Vigo, España |
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Abstract: | IntroductionImportant clinical and epidemiological changes have been observed in lung cancer (LC) in our healthcare area compared to the previous decade. In the last 10 years, specific LC care circuits have been implemented and the active search for cases has been stepped up. The aim of this study was to analyze the progress of these changes over the last 20 years.MethodsThis is a retrospective study comparing clinical and epidemiological changes between 2 historical cohorts of LC patients (1992-1994 [group 1, 164 patients] and 2004-2006 [group 2, 250 patients]) and a current group from the period 2011-2012 (group 3, 209 patients)ResultsTwo hundred and nine (209) LC patients were included in group 3 (2011-2012 period). After comparing groups 3 and 2, a non-significant rise in smoking was observed in women (59% vs 41%, p = .25), while the prevalence of adenocarcinoma was unchanged (45% vs 44%, p = .9). The main changes observed were the increase in cases with previous malignancies (23% vs 16%, p = .04), the rise in patients with no associated LC symptoms (33% vs 16%, p < .001), and an increased number of localized NSCLC (non-small cell LC) diagnoses (42% vs 24% in series 2, p < .001 and 14.2% in series 1, p < .001).ConclusionsThe number of LC patients diagnosed in localized stages has increased significantly. Furthermore, the number of patients with no symptoms associated with LC and with a history of previous malignancy were significantly increased. |
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Keywords: | Cá ncer broncogé nico Cambios epidemioló gicos Tabaquismo Estadio tumoral |
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