| 端粒酶是一种胚胎性肿瘤标志物 |
| |
| 引用本文： | 陈铁河,印木泉,朱炳钗,蔡平. 端粒酶是一种胚胎性肿瘤标志物[J]. 基础医学与临床, 1999, 19(5): 1-T4 |
| |
| 作者姓名： | 陈铁河 印木泉 朱炳钗 蔡平 |
| |
| 作者单位： | 1. 海军医学研究所,上海200433
2. 第二军医大学,上海200433 |
| |
| 摘 要： | 本文对不同时期的人流胚胎组织和肿瘤组织端粒酶活性进行了分析。胚胎组织普遍存在端粒酶活性，其活性水平随胚胎发育时期和组织种类而异。不仅多数恶性肿瘤组织有端粒酶活性，而且某些癌前病变组织如中－重度不典型增生的肠腺癌中也可检测到瑞粒酶活性。结果证实端粒酶是一个新的胚胎性的肿瘤标志物，端粒酶活性分析对肿瘤的早期诊断具有较高的参考价值。
|
| 关 键 词： | 端粒酶 肿瘤标志物 胚胎发育 |
Telomerase as a Fetal Tumor Marker |
| |
| Chen Tiehe,Yin Muquan,Zhu Bingchai,Cai Ping. Telomerase as a Fetal Tumor Marker[J]. Basic Medical Sciences and Clinics, 1999, 19(5): 1-T4 |
| |
| Authors: | Chen Tiehe Yin Muquan Zhu Bingchai Cai Ping |
| |
| Abstract: | Telomerase activities were measured in fetal and tumor tissues. Its level in fetal tissues variedwith different stages of fetal development and in different fetal tissues- Telomerase activity waswidely present in malignant neoplastic tissues and cells, and also in certain cases of moderatelysevere atypical hyperplasia with a tendency of malignant transformation. The results implied that (1)Telomerase activity could be expressed in fetal tissues and was a fetal tumor marker, (2) Teomeraseactivity might appear in precancerous tissues. |
| |
| Keywords: | :Telomerase Tumor marker Fetal development |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
