科素亚对原发性高血压患者胰岛素抵抗的影响

观察科素亚对原发性高血压患者胰岛素抵抗的影响。按世界卫生组织诊断标准,选择原发性高血压患者40例,并与30例健康体检者相对照,原发性高血压患者服科素亚50mg,1次/d,共4周。对照组、原发性高血压组治疗前后均测定空腹静脉血糖、胰岛素及C肽,计算出胰岛素敏感指数。结果显示:原发性高血压组存在胰岛素抵抗,服科素亚4周胰岛素抵抗即有明显改善。

THE EFFECT OF COZAAR ON INSULIN RESISTANCE IN PRIMARRY HYPERTENSION

In this study, the effects of cozaar on insulin resistance in patients with primary hypertension were observed. According to the diagnostic standards of WHO, 40 patients with primary hypertension and 30 healthy people (as control group) were selected. Each patient took cozaar, 50 mg once a day, for 4 weeks. The concentrations of their empty stomach veinal blood sugar, insulin and C peptide were determined before and after the treatment. Then the insulin sensitivity index of the patients was obtained and compared with that of the control. The results showed that the insulin resistance in patients with primary hypertension decreased obviously after they taking cozaar, It is suggested that this drug can improve the insulin resistant in these patiets.