Increased 125I-labelled concanavalin A binding to erythrocytes in diabetes mellitus |
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| Authors: | Dr. Y. Okada T. Arima S. Okazaki K. Nakata T. Yamabuki H. Nagashima |
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| Affiliation: | (1) First Department of Internal Medicine, Okayama University Medical School, Japan;(2) Health Research Center, Okayama University, Japan;(3) Division of Biochemical Oncology, Fred Hutchinson Cancer Research Center, 1124 Columbia Street, 98104 Seattle, Washington, USA |
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| Abstract: | Summary Percentage binding of 125I-labelled concanavalin A to erythrocytes in diabetic patients was significantly higher than that in normal subjects (12.2 ±2.8 versus 8.1±1.8%, mean ± SD, p< 0.001). Insulin-dependent diabetic patients showed significantly higher concanavalin A binding than non-insulin-dependent diabetic subjects (15.0±1.4 versus 11.4±2.5%, p<0.01). There was a highly significant correlation between percentage binding of 125I-labelled concanavalin A and glycosylated haemoglobin. |
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| Keywords: | 125I-labelled concanavalin A human erythrocyte diabetes mellitus glycosylated haemoglobin |
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