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| 河南驻马店市“HIV单阳”夫妻经性传播HIV的调查 | |
| 引用本文： | 葛增,单多,王璐,高省,丁国伟,宋鲁平,周建平,何文生,彭志行.河南驻马店市“HIV单阳”夫妻经性传播HIV的调查[J].疾病控制杂志,2010,14(2):126-129. |
| 作者姓名： | 葛增 单多 王璐 高省 丁国伟 宋鲁平 周建平 何文生 彭志行 |
| 作者单位： | 1. 北京协和医学院公共卫生学院,北京,100730;中国疾病预防控制中心性病艾滋病预防控制中心,北京,100050 2. 中国疾病预防控制中心性病艾滋病预防控制中心,北京,100050 3. 驻马店市疾病预防控制中心,河南,驻马店,463000 4. 南京医科大学公共卫生学院,江苏,南京,211100 |
| 摘 要： | 目的了解河南省驻马店市“HIV单阳”夫妻阴性配偶HIV血清阳转率及HBV、HCV、梅毒感染现状。方法“HIV单阳”夫妻是指夫妻双方中只有一方呈HIV抗体阳性，另一方为阴性。收集“HIV单阳”夫妻成员HIV抗体检测结果及其他相关信息，采集夫妻中HIV阴性配偶的血标本，并检测其HIV、HBV、HCV及梅毒感染状况。结果该市现有“HIV单阳”夫妻4301对，本次调查共采集“HIV单阳”夫妻阴性配偶血样3842份，问卷调查3738人。最近一次性生活安全套使用率为93．1％，85．9％的HIV感染者已发展为艾滋病病人，抗病毒治疗率为77．8％。经检测有50人HIV抗体阳转，血清阳转率为0．65／100人年，抗-HCV阳性率为31．1％、梅毒阳性率为0．2％、乙型肝炎表面抗原（HBsAg）阳性率为5．4％、乙肝“大三阳”（HBsAg、HBeAg、HBcAb均阳性）率为0．8％，乙肝“小三阳”（HBsAg、HBeAb、HBcAb阳性）率为2．9％。结论驻马店市“HIV单阳”夫妻配偶的血清HIV抗体阳转率较低。建议继续加强对该人群的随访、定期检测CD4细胞计数及病毒载量，夫妻间性生活时坚持使用安全套，以控制HIV性传播。 |
| 关 键 词： | “HIV单阳”夫妻 血清阳转率 性传播疾病 |
Survey on HIV infection by heterosexual transmission at families with discordant HIV-infection couples in Zhumadian City, Henan Province |
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| GE Zeng,SHAN Duo,WANG Lu,GAO Xing,DING Guo-wei,SONG Lu-ping,ZHOU Jian-ping,HE Wen-sheng,PENG Zhi-hang.Survey on HIV infection by heterosexual transmission at families with discordant HIV-infection couples in Zhumadian City, Henan Province[J].Chinese Journal of Disease Control and Prevention,2010,14(2):126-129. | |
| Authors: | GE Zeng SHAN Duo WANG Lu GAO Xing DING Guo-wei SONG Lu-ping ZHOU Jian-ping HE Wen-sheng PENG Zhi-hang |
| Institution: | 1. School of Public Health , Peking Union Medical College, Beijing 100730, China ; 2. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China; 3. Zhumadian Center for Disease Control and Prevention, Zhumadian 463000, China ; 4. School of Public Health , Nanjing Medical University, Nanjing 211100, China) |
| Abstract: | Objective To understand HIV seroconversion among HIV discordant couples by heterosexual transmission in Zhumadian City,Henan Province,as well as their hepatitis B virus(HBV),hepatitis C virus(HCV) and syphilis infections.Methods HIV discordant couple means that one partner was HIV positive and the other was negative.Information on HIV infection and other data were collected,and blood specimens of their HIV-negative partners were collected for testing HIV,HBV,HCV and syphilis infections.Results There were 4 ... |
| Keywords: | HIV sero-discordant couples Seroconversion Sexually transmitted disease |
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