早发型重度子痫前期的期待治疗及围产儿预后分析

目的探讨早发型重度子痫前期期待治疗及对围产儿结局的影响。方法对49例早发型重度子痫前期患者进行回顾性分析。根据其确诊孕周分为两组，即A组（20周～31^＋6周）、B组（32周～33^＋6周），比较期待治疗2组的围产儿结局。结果2组孕妇年龄、孕次、收缩压、舒张压比较差异无统计学意义（P〉0．05）；A组确诊孕周、分娩孕周及治疗时间均较B组小（P〈0．05）；A组围产儿体重、身长、双顶径较B组小，差异有统计学意义（P〈0．05）；总围产儿病死率24．49％，A组围产儿病死率、FGR、窒息率较B组升高（P〈0．05）。结论对旱发型重度子痫前期进行期待治疗之前，应对母儿进行细致、充分的评估；早发型重度子痫前期发病越早，终止妊娠时间越早，对围产儿结局影响越大，期待治疗有限。

Analysis of expectant management and perinatal outcome of early onset severe preeclampsia

Objective To explore the impact of expectant management on the perinatal infantile outcome in early onset severe preeclampsia（ES-PE）. Methods The data of 49 cases of early onset severe preeclampsia were retrospectively analyzed. The pregnant women were divided into 2 groups based on pathogenic gestation week ： group A （ 20 weeks 〈 gestation week 〈 32 weeks）, group B （ 32 weeks ≤ gestation week 〈 34 weeks）. The perinatal infantile outcome was compared. Results There were no differences in the mean age, mean gravidity, mean systolic blood pressure,mean diastolic blood pressure between the two groups（ P 〉 0.05 ）. The number of final diagnostic gestational weeks, natal gestational weeks and the time of therapy in group A were significantly less than those in group B （ P 〈 0.05 ）. The number of body weight, body length, and BPD in group A were obviously less than those in group B. （ P 〈 0. 05 ）. The total incidence of perinatal death was 24.49%. The perinatal mortality, morbility of FGR and suffocation rate in group A were significantly higher than those in group B （ P 〈 0.05 ）. Conclusion Sufficient and careful assessment is needed for the maternal and infant status before determining the expectant management for the pregnant women with early onset severe preeclampsia. The earlier onset ES-PE, the earlier the termination of pregnancy,the greater the impact of perinatal outcome. The duration of expectant management should be limited