| 脑震荡患者血清中神经元特异性烯醇化酶的变化及其临床意义 |
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| 引用本文： | 赵鹏洲,罗江兵,吴敬伦,欧英雄,杨本生,余瑞钿,方胜.脑震荡患者血清中神经元特异性烯醇化酶的变化及其临床意义[J].临床和实验医学杂志,2012,11(13):1001-1002. |
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| 作者姓名： | 赵鹏洲 罗江兵 吴敬伦 欧英雄 杨本生 余瑞钿 方胜 |
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| 作者单位： | 南方医科大学附属江门医院神经外科,广东,江门,529051 |
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| 摘 要： | 目的探讨脑震荡患者血清神经元特异性烯化酶(NSE)的变化及其临床意义。方法用酶联免疫吸附测试法测定52例脑震荡患者和30例健康体检者血清NSE水平。结果脑震荡患者在伤后24 h内血清NSE浓度明显高于对照组(P<0.01),经治疗后浓度有降低。结论血清中NSE的检测可反映出脑组织的损伤情况,可作为脑震荡诊断中的神经生化学指标。
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| 关 键 词： | 脑震荡 神经元特异性烯化酶(NSE) 神经生化 |
Investigation of the serum neuron specific enolase in patients with brain concussion and its clinical significance |
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| Institution: | ZHAO Peng-zhou,LUO Jiang-bing,WU jing-lun,et al.Department of Neurosurgery,People＇s Hospital of Jiangmen,Jiangmen Guangdong 529051,China |
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| Abstract: | Objective To investigate the change of serum neuron specific enolase（NSE） in patients with brain concussion and its clinical significance.Methods serum NSE levels were determined using enzyme-linked immunosorbent assay in 52 patients with brain concussion and 30 healthy cases.Results Serum NSE concentrations were significantly higher in patients with brain concussion 24 h after injury than those in control group（P0.01）,after treatment NSE level was reduced.Conclusion Serum NSE detection may reflect brain injury.It can be served as a biomarker for the diagnosis of brain concussion. |
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| Keywords: | Brain concussion Neuron specific enolase Neural biochemical |
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