| 2009～2010年蚌埠地区喹诺酮类抗菌药物不良反应分析 |
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| 引用本文： | 邢蓉,谢冬梅,许健,师佩兰,郭道华,张树强. 2009～2010年蚌埠地区喹诺酮类抗菌药物不良反应分析[J]. 中国药事, 2011, 25(11): 1150-1152 |
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| 作者姓名： | 邢蓉 谢冬梅 许健 师佩兰 郭道华 张树强 |
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| 作者单位： | 1. 蚌埠医学院第一附属医院,蚌埠,233004
2. 蚌埠市食品药品监督管理局 |
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| 基金项目： | 蚌埠市科技局资助科研项目 |
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| 摘 要： | 目的了解蚌埠地区喹诺酮类抗菌药物致药品不良反应（ADR）的发生情况。方法对2009年1月～2010年12月蚌埠地区上报的喹诺酮类抗菌药物致ADR报告,按性别、年龄、给药途径、药品类别、ADR涉及器官或系统及临床表现等进行统计、分析。结果 ADR涉及的喹诺酮类抗菌药物共11种,659例次,发生频次以左氧氟沙星（269例,占40.82%）居首位,其次为氧氟沙星和环丙沙星;主要的ADR类型为皮肤及其附件损害;有2例严重ADR。结论应规范喹诺酮类抗菌药物的临床应用,严格掌握其适应症、禁忌症及用法用量,以减少ADR的发生率。
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| 关 键 词： | 喹诺酮类 抗菌药物 药品不良反应 |
Analysis on ADR of Quinolones Antibiotics Drug in Bengbu City from 2009 to 2010 |
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| Xing Rong,Xie Dongmei,Xu Jian,Shi Peilan,Guo Daohua,Zhang Shuqiang. Analysis on ADR of Quinolones Antibiotics Drug in Bengbu City from 2009 to 2010[J]. Chinese Pharmaceutical Affairs, 2011, 25(11): 1150-1152 |
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| Authors: | Xing Rong Xie Dongmei Xu Jian Shi Peilan Guo Daohua Zhang Shuqiang |
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| Affiliation: | Xing Rong,Xie Dongmei,Xu Jian,Shi Peilan,Guo Daohua and Zhang Shuqiang1(First Affiliated Hospital of Bengbu Medical College,Bengbu 233004,1Bengbu Food and Drug Administration) |
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| Abstract: | Objective To investigate the situation about ADR of quinolones antibiotics in Bengbu city.Methods According to gender,age,drug administration route,drug category,organs or systems that are involved with ADR,clinical manifestations,and so on,statistically analyze reports of quinolones antibiotics drug adverse reactions in Bengbu city reported from Jan 2009 to Dec 2010.Results 11 kinds of quinolones antibiotics drugs were involved in ADR for 659 cases.ADR most occurred in levofloxacin antibiotics(269 cases,ac... |
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| Keywords: | quinolones antibiotics drug ADR |
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