| 保和颗粒质量标准研究 |
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| 引用本文： | 程世云,黄丽丹.保和颗粒质量标准研究[J].中国药事,2011,25(10):1014-1016,1021. |
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| 作者姓名： | 程世云 黄丽丹 |
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| 作者单位： | 安徽省食品药品检验所,合肥,230051 |
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| 摘 要： | 目的建立保和颗粒中山楂、陈皮、半夏和连翘苷的薄层色谱方法及陈皮中橙皮苷的HPLC含量测定的方法。方法色谱柱:Kromasil C18;流动相:乙腈-0.1%磷酸溶液(17∶83);流速:1.0mL.min-1;检测波长:283nm;柱温:30℃。结果橙皮苷在0.04482～0.80676μg范围内呈良好的线性关系(r=0.9995),平均回收率98.98%,RSD=1.93%(n=6)。结论该方法操作简便、重复性好、专属性强,可以用于保和颗粒的质量控制。
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| 关 键 词： | 保和颗粒 质量标准 橙皮苷 薄层色谱 HPLC |
Study on Quality Standard for Baohe Granules |
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| Cheng Shiyun,Huang Lidan.Study on Quality Standard for Baohe Granules[J].Chinese Pharmaceutical Affairs,2011,25(10):1014-1016,1021. |
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| Authors: | Cheng Shiyun Huang Lidan |
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| Institution: | Cheng Shiyun and Huang Lidan(Anhui Provincial Institute for Food and Drug Control,Hefei 230051) |
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| Abstract: | Objective To identify Crataegi fructus,Citri reticulatae pericarpium,Pinelliae rhizome and Forsythin by TLC method and to determine hesperidin in Baohe Granules by HPLC.Methods Using a Kromasil C18 column,a minxture of acetonitrile-0.1%H3PO4（17∶83）with the flow rate of 1.0mL·min-1;the detective wavelength was 283nm and the column temperature was 30℃.Results The linear range of hesperidin was 0.04482~0.80676μg（r=0.9995）.The average recovery rate was 98.98% with RSD=1.93%（n=6）.Conclusion The established method is rapid,accurate,reproducible and specific.It can be used for routine quality control of Baohe Granules. |
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| Keywords: | Baohe Granules quality standard hesperidin TLC HPLC |
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