| 2型糖尿病微血管病变患者血浆同型半胱氨酸、胱抑素C水平及血液流变学指标变化 |
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| 引用本文： | 刘菊,梅群超.2型糖尿病微血管病变患者血浆同型半胱氨酸、胱抑素C水平及血液流变学指标变化[J].微循环学杂志,2012,22(3):39-41,6,10. |
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| 作者姓名： | 刘菊 梅群超 |
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| 作者单位： | 华中科技大学同济医学院附属中西医结合医院,武汉市第一医院老年病科,武汉,430022 |
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| 摘 要： | 目的:观察2型糖尿病(T2DM)微血管病变患者血浆同型半胱氨酸(Hcy)、胱抑素C(CysC)水平及血液流变学指标的变化。方法:T2DM患者120例,按有无微血管病变分为糖尿病无微血管病变组(A组,62例)和糖尿病并微血管病变组(B组,58例),检测两组病人的血浆Hcy、CysC水平和血液流变学指标并进行组间比较分析。结果:与A组比较,B组血浆Hcy、CysC、全血粘度、血浆粘度、红细胞压积、红细胞聚集指数均明显升高,差异有统计学意义(P<0.01)。结论:高Hcy、CysC及高粘血症参与了糖尿病微血管病变的发生和发展。
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| 关 键 词： | 2型糖尿病微血管病变 胱抑素C 同型半胱氨酸血症 血液流变学 |
Change of Plasma Homolysteine and Cystatin C and Blood Rheology in Type 2 Diabetic Microagniopathy Patients |
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| Liu Ju, Mei Qunchao.Change of Plasma Homolysteine and Cystatin C and Blood Rheology in Type 2 Diabetic Microagniopathy Patients[J].Chinese Journal of Microcirculation,2012,22(3):39-41,6,10. |
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| Authors: | Liu Ju Mei Qunchao |
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| Institution: | Department of Geriatrics, The Hospital of Integrative Medicine,Tongji Medical College of Huazhong University of Science and Technology, The First Hospital of Wuhan,Wuhan 430022,China |
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| Abstract: | Objective: To observe the clinical significance of plasma homolysteine(Hcy),cystatin C and blood rheology in type 2 diabetic(T2DM) microagniopathy patients. Method: 120 patients with T2DM were divided into two groups, one group was non-microangiopathy(group A,n=62) and the other group was microangiopathy (group B,n=58).All patients’plasma Hcy,cystatin C and blood rheology were measured. Results: The levels of plasma Hcy,cystatin C and blood rheology in group B were significantly higher than the target level of the non-microangiopathy group,there was significant difference(P<0.01). Conclusion: There is relationship between Hcy,cystatin C,hyperviscosity and diabetic cmicroangiopathy. |
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| Keywords: | Type 2 diabetic microagniopathy Cystatin C Homolysteine Blood rheology |
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