肌炎特异性抗体与多发性肌炎/皮肌炎的研究进展

多发性肌炎和皮肌炎是骨骼肌受累为主要表现的自身免疫性疾病,通常合并其他器官系统损害,包括关节、肺、心脏、胃肠道等.除了临床症状、体征、血生化、肌电图及肌肉病理诊断方法外,进行肌炎抗体检测也很有必要.多发性肌炎/皮肌炎病人所存在的多种肌炎抗体对疾病的诊断、临床分型、判断疾病活动度、预后均有一定的帮助.

Research progress of myositis specific antibody and polymyositis/dermatomyositis

Polymyositis and dermatomyositis are autoimmune diseases mainly manifested by skeletal muscle involvement, which are usually combined with other organ system damage, including joints, lungs, heart, gastrointestinal tract, etc. In addition to clinical symp-toms, signs, blood biochemistry, electromyography and muscle pathology diagnostic detection, it is also necessary to perform myositis antibody detection. The existence of multiple myositis antibodies in patients with polymyositis/dermatomyositis is helpful for the diagno-sis, clinical classification, disease activity and prognosis.