超声检测缺氧缺血性脑病早产儿脑血流改变

目的探讨早产儿缺氧缺血性脑病（HIE）早期脑血流改变及其意义。方法应用彩色多普勒超声诊断仪对86例HIE早产儿于生后20～24小时内检测其MCA、ACA、LA、FIA的收缩期峰值流速（Vs）、舒张末期速度（Vd）及阻力指数（RI），并与正常对照组88例进行比较。结果①血流速度的变化：生后20～24小时内正常组及HIE组血流速度均升高，与自身对比差异有显著性（P〈0．05），HIE组FIA—Vd明显高于对照组。②血管阻力指数变化：生后20—24小时内HIE组与对照组比较RI差异无显著性（P〉0．05）。结论HIE组于20～24小时已出现脑血流量的代偿改变，但其意义须结合之前检测对比分析。

Ultrasonographic detection of the early changes of cerebral hemodynamics in premature infants with hypoxic-ischemic encephalopathy

Objective To explore the early changes of cerebral blood flow in premature infants with hypoxic-ischemic encephalopathy (HIE).Methods The peak systolic velocity (Vs),end diastolic velocity (Vd),and resistance index (RI) of middle cerebral artery (MCA),anterior cerebral artery (ACA),lenticulostriate artery (LA),and frontal intermediomedial artery (FIA)were detected in 86 premature infants with HIE by color Doppler within 20 - 24 hours after birth.The results were compared with those from 88 control subjects.Results The blood flow velocity increased significantly within 20 - 24 hours after birth in both groups,as compared with the baseline.Vd of FIA was significantly greater in the HIE group than in the control group.There was no significant difference in RI between the HIE group and the control group within 20-24 hours after birth.Conclusions A compensatory change of cerebral blood flow develops in premature infants with hypoxic-ischemic encephalopathy within 20 to 24 hours after birth,but this change has to be compared with the baseline to determine its significance.