| 逐步回归分析法研究影响山楂叶混合粉压缩成型性的粉体学性质 |
| |
| 引用本文： | 罗娟,蒋且英,廖正根,李哲,曾荣贵,吕丹,梁新丽,孔小强.逐步回归分析法研究影响山楂叶混合粉压缩成型性的粉体学性质[J].中国实验方剂学杂志,2016,22(12):7-12. |
| |
| 作者姓名： | 罗娟 蒋且英 廖正根 李哲 曾荣贵 吕丹 梁新丽 孔小强 |
| |
| 作者单位： | 江西中医药大学 现代中药制剂教育部重点实验室, 继续教育学院, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 继续教育学院, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 继续教育学院, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 继续教育学院, 南昌 330004;郑州市妇幼保健院, 郑州 450012,江西中医药大学 现代中药制剂教育部重点实验室, 继续教育学院, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 继续教育学院, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 继续教育学院, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 继续教育学院, 南昌 330004 |
| |
| 基金项目： | 国家自然科学基金项目(81160522);"赣鄱 555"工程领军人才培养项目 |
| |
| 摘 要： | 目的:研究山楂叶混合粉的粉体学性质对其压缩成型性的影响。方法:以山楂叶50%乙醇提取的浸膏粉为模型药物,采用3种制备工艺,分别与2种辅料(微晶纤维素、可溶性淀粉)按质量比1∶0.5,1∶1,1∶2混合制备混合粉体,得18种山楂叶混合粉体。以抗张强度-压力回归方程中斜率为指标评价山楂叶混合粉的压缩成型性,运用逐步回归分析法研究山楂叶混合粉压缩成型性与粉体学性质之间的相关性。结果:山楂叶混合粉压缩成型性与粉体的振实密度(ρ_t),累计孔体积(PV),含水量(MC)及临界相对湿度(CRH)呈正相关,与粉体的50%通过粒径(D50),粒径距(Span),松散密度(ρ_b),Carr指数(CI),豪斯纳比率(HR)及比表面积(SSA)呈负相关。结论:ρ_b,ρ_t,Span,MC和CRH是影响山楂叶混合粉压缩成型性的关键粉体学性质。
|
| 关 键 词： | 山楂叶 混合粉 粉体学性质 压缩成型性 抗张强度 逐步回归分析 |
| 收稿时间： | 2015/9/17 0:00:00 |
Effects of Key Micromeritic Properties on Compactibility of Crataegi Folium Blended Powder by Stepwise Regression Analysis |
| |
| LUO Juan,JIANG Qie-ying,LIAO Zheng-gen,LI Zhe,ZENG Rong-gui,LYU Dan,LIANG Xin-li and KONG Xiao-qiang.Effects of Key Micromeritic Properties on Compactibility of Crataegi Folium Blended Powder by Stepwise Regression Analysis[J].China Journal of Experimental Traditional Medical Formulae,2016,22(12):7-12. |
| |
| Authors: | LUO Juan JIANG Qie-ying LIAO Zheng-gen LI Zhe ZENG Rong-gui LYU Dan LIANG Xin-li and KONG Xiao-qiang |
| |
| Institution: | School of Continuing Education, Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China,School of Continuing Education, Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China,School of Continuing Education, Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China,School of Continuing Education, Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China;Women and Infants Hospital of Zhengzhou, Zhengzhou 450012, China,School of Continuing Education, Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China,School of Continuing Education, Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China,School of Continuing Education, Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China and School of Continuing Education, Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China |
| |
| Abstract: | |
| |
| Keywords: | Crataegi Folium blended powder micromeritic properties compactibility tensile strength stepwise regression analysis |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国实验方剂学杂志》浏览原始摘要信息 |
| 点击此处可从《中国实验方剂学杂志》下载免费的PDF全文 |
|
