OSAHS患者上气道磁共振影像研究

目的：研究清醒状态下阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者与正常健康人在磁共振（MRI）上的上气道参数差异和阻塞平面情况。方法：OSAHS患者和正常健康人各20例，进行MRI检查和测量。结果：①．OSAHS组RP区，RG区气道截面积明显小于对照组（p〈0．01）；②．OSAHS组RP区、RG区、EPG区气道前后径／左右径（AP／LR）比值均明显大于对照组（p〈0．05）；③．OSAHS组RP区、RG区、EPG区咽侧壁厚度均明显大于对照组（p〈0．05）；RG区，EPG区咽后壁厚度明显大于对照组（p〈0．01）；④．OSAHS组软腭长度、厚度和截面积均明显大于对照组（P〈0．05）：⑤．95％的OSAHS患者在清醒状态下即可见上气道阻塞平面。70％的OSAHS患者为多平面阻塞，阻塞多发生于软腭后区。结论：OSAHS患者上气道参数与正常健康人有显著性差异。软腭后区是OSAHS患者上气道最狭窄的部位。

Study of upper airway image with MRI in obstructive sleep apnea hypopnea syndrome

Objective:To investigate the differences of upper airway indices and locate the site(s) of obstruction in obstructive sleep apnea hypopnea syndrome(OSAHS) with magnetic resonance image (MRI). Method:40 subjects,in which 20 subjects diagnosed as OSAHS polysomnographically as a experimental group,and 20 nonsnoring age-sex matched normal subjects as a control group,were used in this study. MRI was taken for the patients with OSAHS and those in control. Result:In OSAHS group,the AP/LR ratio and the thickness of lateral pharyngeal wall in RP,RG,EPG regions,the length,thickness and cross-sectional area of the soft palate were statistically larger than those of the control group(p < 0.05). The cross-sectional area of RP and RG regions were statistically smaller than that of the control group(p < 0.01). The thickness of posterior pharyngeal wall in RG and EPG regions was statistically larger than that of the control group(p < 0.01). Obstructive site(s) existed in 95% awake OSAHS patients and multiple sites in 70%. Velopharyngeal region was the most narrow site of upper airway in OSAHS patients. Conclusion:Velopharyngeal region was the most narrow site of upper airway in OSAHS patients.