Epidemiologic Study of Radiotherapy Use in China in Patients With Breast Cancer Between 1999 and 2008 |
| |
Authors: | Shu-Lian Wang Ye-Xiong Li Bao-Ning Zhang Jing Li Jin-Hu Fan Jian-Jun He Qing-kun Song Pin Zhang Shan Zheng Bin Zhang Hong-Jian Yang Xiao-Ming Xie Zhong-Hua Tang Hui Li Jia-Yuan Li You-Lin Qiao |
| |
Affiliation: | 1. University Hospital Basel (UHB), Breast Center, Basel,;2. Department of Gynecology and Obstetrics, UHB, Basel;3. Department of Gynecology and Obstetrics, Cantonal Hospital Winterthur, Winterthur,;4. Department of Oncology, UHB, Basel, Switzerland |
| |
Abstract: | BackgroundTo investigate the use of radiotherapy (RT) in China in patients with breast cancer over a 10-year period. A hospital-based, nationwide, multicenter, retrospective epidemiologic study of women with primary breast cancer was conducted.Patients and MethodsPatients were selected randomly in 7 hospitals from 1999 to 2008. Data on overall RT, postmastectomy RT (PMRT), RT after conservative breast surgery (PBRT) and palliative RT (PRT) were recorded. RT use was analyzed, and differences were compared by using the Cochran-Armitage trend test and the χ2 test. A total of 3732 patients were included: 1009 (27%) received RT, including 688 (18.4%) PMRT, 170 (4.6%) PBRT, 86 (2.3%) PRT, 47 (1.3%) both PMRT and PRT, and 18 (0.5%) other RT.ResultsOverall use of RT increased significantly from 1999 to 2008 (2P < .001). There was a slight but significant increase in PMRT (2P = .012) and a 10-fold increase in PBRT (2P < .001); use of PRT was relatively constant (2P = .777). There was a significant difference among regions in the use of RT, PMRT, PBRT, and PRT (2P < .01). Of patients with stage III disease, 51.6% and of those with node-positive stage II disease treated by radical mastectomy, 21% had received PMRT. In patients treated by using breast conservative surgery, 83.7% received PBRT, which was not affected by stage.ConclusionIn summary, in China, the overall use of RT in patients with breast cancer was quite low, but there was an increasing trend in those treated between 1999 and 2008. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|