Paravalvular regurgitation after transcatheter aortic valve replacement: Diagnosis,clinical outcome,preventive and therapeutic strategies |
| |
| Authors: | Danny Dvir Israel M Barbash Itsik Ben-Dor Rebecca Torguson Salem Badr Sa'ar Minha Lakshmana K Pendyala Joshua P Loh Augusto D Pichard Ron Waksman |
| |
| Institution: | 1. Department for the Surgical Therapy of End-stage Heart Failure and Mechanical Circulatory Support, Heart and Vascular Center Duisburg, Duisburg, Germany;2. Department of Thoracic and Cardiovascular Surgery, RWTH University Aachen, Aachen, Germany;1. Department of Cardiology, Lankenau Medical Center, Wynnewood, Pennsylvania;2. Thomas Jefferson University, Philadelphia, Pennsylvania;3. Medstar Heart Institute, Washington Hospital Center, Washington, DC;4. Department of Medicine, Albert Einstein College of Medicine, Bronx, New York;2. Department of Rheumatology, Immunology and Allergy, Christchurch Hospital, Christchurch, New Zealand |
| |
| Abstract: | Paravalvular regurgitation is a common, potentially life-threatening complication of transcatheter aortic valve replacement. Previous studies report a 65%–94% rate of paravalvular leakage after transcatheter implantation, mostly of mild degree. The rate of significant (≥ + 2) paravalvular regurgitation varies in large clinical trials, and is associated with worse clinical outcome. There is less agreement regarding the significance of mild regurgitation (grade 1 +). There are anatomical and procedural correlates for paravalvular leak—most importantly, severe valve calcification, patient prosthetic mismatch, and device malposition. The following review details the current knowledge on paravalvular regurgitation after transcatheter aortic valve replacement, including diagnosis, correlates, clinical outcome, preventive and therapeutic strategies related to this complication. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
