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| 子宫内膜癌中TRAIL诱骗受体的表达研究 | |
| 引用本文： | 李榕,姬秋和,刘雪松,陈健康,马福成,张南雁,金伯泉. 子宫内膜癌中TRAIL诱骗受体的表达研究[J]. 医学研究生学报, 2003, 16(7): 489-490,495,F002 |
| 作者姓名： | 李榕 姬秋和 刘雪松 陈健康 马福成 张南雁 金伯泉 |
| 作者单位： | 1. 第四军医大学,西京医院内分泌科,陕西西安,710032 2. 第四军医大学,免疫教研室,陕西西安,710032 3. 第四军医大学,教学实验中心,陕西西安,710032 4. 第四军医大学,病理教研室,陕西西安,710032 |
| 摘 要： | 目的：了解子宫内膜癌中肿瘤坏死因子相关凋亡诱导配体（TRAIL）诱骗受体（DcR1、DcR2)的表达情况。方法：用免疫组化的方法观察13例子宫内膜癌和7例正常子宫内膜标本中DcR1、DcR2的表达，分析其在子宫内膜癌中的含量变化。结果：子宫内膜癌中DcR1、DcR2的表达水平较正常子宫内膜显著减低。结论：DcR1、DcR2在子宫内膜癌中的低表达可能与其发病机制有关，可能对防止子宫内膜癌变具有一定作用。 |
| 关 键 词： | 子宫内膜癌 肿瘤坏死因子相关凋亡诱导配体 诱骗受体 |
| 文章编号： | 1008-8199(2003)07-0489-02 |
The expressions of decoy receptors of TRAIL in carcinoma of endometrium |
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| LI Rong ,JI Qiu he ,LIU Xue song ,CHEN Jian kang ,MA Fu cheng ,ZHANG Nan yan ,JIN Bo quan. The expressions of decoy receptors of TRAIL in carcinoma of endometrium[J]. Bulletin of Medical Postgraduate, 2003, 16(7): 489-490,495,F002 | |
| Authors: | LI Rong JI Qiu he LIU Xue song CHEN Jian kang MA Fu cheng ZHANG Nan yan JIN Bo quan |
| Affiliation: | LI Rong 1,JI Qiu he 1,LIU Xue song 2,CHEN Jian kang 3,MA Fu cheng 4,ZHANG Nan yan 1,JIN Bo quan 2 |
| Abstract: | Objectives:To determine the expressions of decoy receptors (DcR1 and DcR2) of TRAIL in carcinoma of endometrium. Methods:The expressions of DcR1 and DcR2 in endometrium tissues from 13 carcinoma of endometrium and 7 normal endometrium were detected by immunohistochemical staining.Results: The expressions of DcR1 and DcR2 in carcinoma of endometrium were much lower than in normal endometrium. Conclusions:The decreasing of DcR1 and DcR2 in carcinoma of endometrium may be concerned with its pathogenesis, which may be related to the prevention of endometrium from carcinomatous change. |
| Keywords: | Carcinoma of endometrium TRAIL Decoy receptor |
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