| 强心胶囊对大鼠心肌再灌注心律失常的影响 |
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| 引用本文： | 吴英,袁秉祥.强心胶囊对大鼠心肌再灌注心律失常的影响[J].西北药学杂志,2001,16(1):23-24. |
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| 作者姓名： | 吴英 袁秉祥 |
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| 作者单位： | 西安交通大学药学院药理教研室 |
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| 摘 要： | 观察强心胶囊对大鼠心肌再灌注时心律失常发生率及心肌组织 ＳＯＤ活性和 ＭＤＡ含量的影响。实验表明，缺血４０ｍｉｎ，再灌注３０ｍｉｎ后强心胶囊０．６ｇ／ｋｇ·ｄ；能明显减轻缺血再灌注心律失常的发生，显著提高大鼠心肌组织ＳＯＤ活性并减少ＭＤＡ的生成。
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| 关 键 词： | 强心胶囊 心肌缺血再灌注 超氧化物歧化酶 脂质过氧化 心律失常 |
| 修稿时间： | 2000年8月22日 |
Effects of Qiangxin capsules on myocardial reperfusion arrhythmias in rats |
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| Wu Ying,Yuan Bingxiang.Effects of Qiangxin capsules on myocardial reperfusion arrhythmias in rats[J].Northwest Pharmaceutical Journal,2001,16(1):23-24. |
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| Authors: | Wu Ying Yuan Bingxiang |
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| Abstract: | To investigate the effects of Qiangxin capsules on myocardial reperfusion arrhythmias in rats. When myocardial ischemia reperfusion models were established in SD rats, we observed the protective effect of prophylactic use of Qiangxin capsules(0.6g/kg daily for 6 days). After 40min ischemia and 30min reperfusion, the results showed the obvious decrease of the occurrences of arrhythmia and significant increase of the SOD activity and reduce of the production of MDA in rat. |
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| Keywords: | Qiangxin capsules myocardial ischemic reperfusion superoxide dismutase lipid peroxide arrhythmia |
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