| 慢性重型乙型肝炎患者血清白介素-18与一氧化氮检测的临床意义 |
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| 引用本文： | 彭晓明,刘娅,王煜,向洪涛,王海燕. 慢性重型乙型肝炎患者血清白介素-18与一氧化氮检测的临床意义[J]. 现代医药卫生, 2011, 27(12): 1765-1766 |
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| 作者姓名： | 彭晓明 刘娅 王煜 向洪涛 王海燕 |
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| 作者单位： | 1. 宁夏医科大学,宁夏,银川,750004
2. 宁夏医科大学附属医院感染疾病科,宁夏,银川,750004 |
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| 摘 要： | 目的:探讨慢性重型乙型肝炎血清中白介素-18与一氧化氮的水平检测的临床意义.方法:设立正常对照组42例、慢性乙型肝炎组36例和慢性重型乙型肝炎组31例,用ELISA方法检测血清中白介素-18水平,同时用硝酸还原酶法检测血清中一氧化氮水平,观察各组白介素-18和一氧化氮的水平.结果:慢性重型乙型肝炎组和慢性乙型肝炎组血清中白介素-18、一氧化氮水平较正常对照组均升高,慢性重型乙型肝炎组较慢性乙型肝炎组升高更显著,各组间比较均差异有统计学意义(P均＜0.05).结论:白介素-18、一氧化氮升高是慢性重型乙型肝炎病情加重的原因之一,检测血清中白介素-18、一氧化氮可作为判断慢性重型乙型肝炎患者病情严重程度的指标.
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| 关 键 词： | 慢性重型乙型肝炎 白介素-18 一氧化氮 |
Clinical significance of measuring serum IL-18 and NO in chronic severe hepatitis B |
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| PENG Xiao-ming , LIU Ya , WANG Yu , XIANG Hong-tao , WANG Hai-yan. Clinical significance of measuring serum IL-18 and NO in chronic severe hepatitis B[J]. JOURNAL OF MODERN MEDICINE & HEALTH, 2011, 27(12): 1765-1766 |
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| Authors: | PENG Xiao-ming LIU Ya WANG Yu XIANG Hong-tao WANG Hai-yan |
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| Affiliation: | PENG Xiao-ming1,LIU Ya2,WANG Yu2,XIANG Hong-tao1,WANG Hai-yan1(1.Ningxia Medical University,Yinchuan,Ningxia 750004,China,2.Department of Infection,Affiliated Hospital of Ningxia Medical University,China) |
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| Abstract: | Objective:To investigate the clinical significance of measuring the levels of serum IL-18 and NO in chronic severe hepatitis B patients.Methods:Serum IL-18 was detected by ELISA method and serum NO by nitrate reductase method in 42 cases of normal control,36 cases of chronic hepatitis B and 31 cases of chronic severe hepatitis B.The levels of serum IL-18 and NO were observed in each group.Results:The levels of serum IL-18 and NO in chronic severe hepatitis B group and chronic hepatitis B group were higher t... |
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| Keywords: | Chronic severe hepatitis B IL-18 NO |
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