Epidermolytic variant of hereditary palmoplantar keratoderma |
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| Authors: | CHARLES CAMISA HOMER WILLIAMS |
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| Institution: | Department of Medicine, Division of Dermatology, Ohio State University, Columbus, Ohio, U.S.A. |
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| Abstract: | The seventh family with autosomal dominant epidermolytic palmoplantar keratoderma is reported. The lesions are clinically indistinguishable from Unna-Thost disease but resemble epidermolytic hyperkeratosis (bullous ichthyosiform erythroderma) histopathologically. A skin biopsy is essential for making the correct diagnosis. One of our patients was treated with isotretinoin for 13 weeks without significant improvement. |
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