The role of gallium 67 imaging in non-Hodgkin's lymphoma of the gastrointestinal tract |
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Authors: | Masaaki Kataoka Masashi Kawamura Takaharu Tsuda Hisao Itoh Akira Komatsu Shuji Tanada Atsushi lio Ken Hamamoto |
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Affiliation: | (1) Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, 791-02 Onsen-gun, Ehime, Japan |
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Abstract: | To evaluate the clinical usefulness of gallium 67 imaging in the detection of gastrointestinal (GI) non-Hodgkin's lymphoma (NHL) and in the assessment of the therapeutic effects, images were reviewed in 24 cases (25 lesions: stomach, 20; ileum, 2; and terminal ileum and/or cecum, 3) and were compared using barium studies and, in 16 cases, computerized tomography (CT). In all, 23 (92.0%) of the 25 lesions were detected by67Ga citrate imaging, the barium studies detected all 25, and CT detected 15 of 16 lesions (93.8%). The two lesions not identified by imaging and the one not found by CT were the smallest of all. In 2 (8.7%) of the 23 lesions positively identified by67Ga-citrate imaging, both CT and imaging revealed the extent of the tumor more accurately than did the barium studies. In all but one of the patients, a close correlation existed between the imaging results and the therapeutic effects. These data suggest that67Ga imaging is useful in conjunction with CT and barium studies for the detection of GI NHL and for the assessment of both the spatial extent of disease and the therapeutic effects, although a lack of67Ga uptake after therapy does not always indicate a good therapeutic effect. |
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Keywords: | Gallium 67 imaging Computerized tomography Barium study Non-Hodgkin's lymphoma Gastrointestinal tract |
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