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阿昔洛韦分散片溶出度考察
引用本文:易涛,汤韧,符旭东,张宜.阿昔洛韦分散片溶出度考察[J].中国临床药学杂志,2001,10(1):19-21.
作者姓名:易涛  汤韧  符旭东  张宜
作者单位:广州军区武汉总医院药剂科 武汉 430070
摘    要:目的:考察自行研制的阿昔洛韦分散片的溶出度。方法:采用溶出度测定小杯法,以水为溶剂,测定阿昔洛韦分散片同一批号不同组次和不同批号的溶出度,并与两种市售阿昔洛韦普通片比较。结果:阿昔洛韦分散片的溶出度均一性好,累积溶出百分率在20min内可达90%。结论:阿昔洛韦分散片的溶出度比普通片快。

关 键 词:阿昔洛韦分散片  阿昔洛韦普通片  溶出度  比较  抗病毒药
文章编号:1007-4406(2001)01-019-03

Investigation on the dissolution of dispersible acyclovir tablets
Yi Tao,Tang Ren,Fu Xudong,Zhang Yi.Investigation on the dissolution of dispersible acyclovir tablets[J].Chinese Journal of Clinical Pharmacy,2001,10(1):19-21.
Authors:Yi Tao  Tang Ren  Fu Xudong  Zhang Yi
Abstract:AIM: To investigate the quality of dispersible acyclovir tablets. METHODS: Investigation on the dissolution of the tablets was made using distilled water as solvent, detection wavelength was 252 nm. The dissolution of 2 kinds of ordinary acyclovir tablets was compared with dispersible acyclovir tablets. RESULTS: The dissolved amount of the dispersible acyclovir tablets was more than 90% within 20 min and more than that of the ordinary acyclovir tablet. CONCLUSION: It is suggested that the dissolution of dispersible acyclovir tablets is better than that of ordinary acyclorvir tablets.
Keywords:dispersible acyclovir tablet  ordinary acyclorvir tablet  dissolution
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