| 男性类风湿关节炎患者的血清性激素水平测定及其临床意义 |
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| 引用本文： | 周蕾,董笑影,巩路,李宝全,石秋英.男性类风湿关节炎患者的血清性激素水平测定及其临床意义[J].山东医药,2002,42(18):1-2. |
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| 作者姓名： | 周蕾 董笑影 巩路 李宝全 石秋英 |
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| 作者单位： | 1. 天津医科大学总医院,天津,300052
2. 天津医院 |
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| 摘 要： | 采用放射免疫法检测34例男性类风湿关节炎（RA）患者（RA组）的血清雌二醇（E2），睾酮（T），硫酸脱氢表雄酮（DHEAS）水平，并与30例健康男性（对照组）作对照。结果发现患者血清T，DHEAS水平明显低于正常对照组（P＜0．05，P＜0．001），而E2水平虽低于对照组，但无显著差异（P＞0．05），提示雄激素减低在男性RA的发病中起一定的作用。
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| 关 键 词： | 类风湿关节炎 性激素 男性 测定 |
| 修稿时间： | 2002年7月1日 |
Detection and significance of serum levels of sex hormones in male patients with rheumatoid arthritis |
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| Zhou lei,Dong Xiaoying,Shi Qiuying,et al.Detection and significance of serum levels of sex hormones in male patients with rheumatoid arthritis[J].Shandong Medical Journal,2002,42(18):1-2. |
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| Authors: | Zhou lei Dong Xiaoying Shi Qiuying |
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| Abstract: | To investigate the role of sex hormones in the pathogenesis of rheumatoid arthritis (RA), the serum levels of estradiol(E 2),testosterone (T) and dehydroepiandrosterone sulfate (DHEAS) were measured in 34 male patients with RA and 30 normal controls by radioimmunoassay. The serum levels of T and DHEAS in male RA patients were significantly lower than that of the controls (P<0.05, P<0.001), the level of E 2 was decreased but not significantly from the controls (P>0.05). This suggests the invasion of RA is a possible pathogenic role of decreased levels of the androgens . |
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| Keywords: | Rheumatoid arthritis Sex hormones |
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