脑卒中患者伴发焦虑和抑郁性障碍的临床研究

目的:研究脑卒中患者焦虑和抑郁性障碍的发生率和治疗效果.方法:用汉密尔顿焦虑量表(HAMA)和抑郁量表(HAMD)评估200例脑卒中病人,对伴有焦虑、抑郁性障碍者,用苯二氮(艹)/(卓)类、氟西汀治疗.结果:200例患者中,焦虑、抑郁性障碍的发生率分别为49%、37.5%,治疗好转率分别为82.3%、85.7%.治疗后HAMA和HAMD积分较治疗前明显减少(P＜0.01).结论:抑郁性障碍在脑卒中患者中的发生率高,抗焦虑、抑郁治疗的疗效显著.

ON THE ANXIETY AND DEPRESSION IN PATIENTS WITH STROKE

Objective:To study the frequency and therapeutic effect of anxious and depressive disorders in patients with stroke.Methods:200 patients were assessed with Hamilton rating scale for anxiety(HAMA) and Hamilton rating scale for depression (HAMD).The patients with anxious and depressive disorders were treated with antianxiety agents and antidepressants such as benzodiazepines and fluoxetine.Results:In the 200 patients,the frequencies of anxious and depressive disorders were 49% and 37 5% ,respectively,recovery rates of treatment were 82 3% and 85 7%, respectively.The scores of HAMA and HAMD were much lower after treatmen than before treatment ( P <0 01).Conclusion:The frepuencies of anxious and depressive disorders in patients with stroke are very high,and the therapeatic effect of antianxiety agents and antidepressants is obvious.