| 雌激素与甲状腺癌的关系 |
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| 引用本文： | 张璐,刘跃武. 雌激素与甲状腺癌的关系[J]. 基础医学与临床, 2010, 30(7): 782-784 |
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| 作者姓名： | 张璐 刘跃武 |
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| 作者单位： | 中国医学科学院,北京协和医学院,北京协和医院,基本外科,北京,100730 |
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| 摘 要： | 雌激素主要通过其特异受体作用于甲状腺癌细胞。雌激素可以通过其特异受体即雌激素受体（ER）结合雌激素反应因子，激活多种基因影响甲状腺癌细胞生长。以及雌激素通过丝裂原活化蛋白激酶(MAPK)信号转导途径刺激甲状腺癌细胞生长。
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| 关 键 词： | 甲状腺癌 雌激素 雌激素受体 |
The relationship between estrogen and thyroid carcinoma |
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| ZHANG Lu,LIU Yue-wu. The relationship between estrogen and thyroid carcinoma[J]. Basic Medical Sciences and Clinics, 2010, 30(7): 782-784 |
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| Authors: | ZHANG Lu LIU Yue-wu |
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| Abstract: | Estrogen exclusively influences the growth of thyroid carcinoma cells by estrogen receptors. Estrogen binds estrogen response element by estrogen receptor, then activating many genes ，these genes involve the growth of thyroid carcinoma cells . And estrogen stimulates the growth of thyroid carcinoma cells by the mitogen activated protein kinases signal transduction pathway. |
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| Keywords: | thyroid carcinoma estrogen estrogen receptor |
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