| 感染旋毛虫小鼠外周血有核细胞及抗体水平的动态观察 |
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| 引用本文： | 申丽洁,罗志勇,李伟. 感染旋毛虫小鼠外周血有核细胞及抗体水平的动态观察[J]. 大理医学院学报, 2000, 0(2) |
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| 作者姓名： | 申丽洁 罗志勇 李伟 |
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| 作者单位： | 大理医学院寄生虫学教研室!大理671000(申丽洁，李伟)，大理医学院临床医学系(罗志勇) |
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| 摘 要： | 目的 :探讨旋毛虫感染过程中血清抗体和有核细胞变化的规律。方法 :采用ELISA检测血清IgG抗体 ,血涂片瑞氏染色计数各类有核细胞百分数。结果 :旋毛虫感染小鼠血清IgG抗体水平逐渐升高 ,感染后42d达观察期间的最高值 ;嗜酸性粒细胞和中性粒细胞比例高于感染前 ,单核细胞和淋巴细胞比例则低于感染前。结论 :提示嗜酸性粒细胞是旋毛虫感染免疫中起主要作用的细胞 ,抗旋毛虫感染免疫是体液免疫和细胞免疫协同作用的
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| 关 键 词： | 旋毛虫 抗体 嗜酸性粒细胞 感染免疫 |
Dynamic Observation of the Nucleated Cells and Antibody from Mice Infected with Trichinella Spiralis |
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| ShenLijieLuoZhiyong LiWei. Dynamic Observation of the Nucleated Cells and Antibody from Mice Infected with Trichinella Spiralis[J]. Journal of Dali Medical College, 2000, 0(2) |
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| Authors: | ShenLijieLuoZhiyong LiWei |
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| Abstract: | Objective:Toinvestigatethechangerulesoftheserumantibodyandperipheralbloodnucleated cellsinTrichinellaspiralisinfection.Methods:TheserumIgGwasdeterminedbyELISA,andtheclassification andpercentageofnucleatedcellsinbloodsmearswerecounted.Results:AfterthemiceinfectedwithTrichinella spiralis,thelevelofIgGincreasedgradually,andreacheditspeakin42eddayafterinfection(observed6weeks altogether).Thepercentagesofneutrophilandeosinophilwerehigherthanthoseofbeforeinfection,buttheper centagesofmonocyteandlymphocytewerelowerthanthoseofbeforeinfection.Conclusions:Theresultssuggest thateosinophilsandneutrophilswerethemostimportantcellsinTrichinaspiralsinfectiveimmunity.Theprotective immunityofagainstTrichinellaspiralisinfectionwascellularimmunitycooperationwithhumoralimmunity. |
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| Keywords: | Trichinella spiralis Antibody Eosinophil Infective Immunity |
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