Hypoglycaemia and seizures in large-for-gestational-age (LGA) full-term neonates

AIM/METHODS: To assess the risk of hypoglycaemia-associated seizures in large-for-gestational-age (LGA) full-term neonates data from the Netherlands Perinatal Registry were analysed. RESULTS: From 1997 to 2002 hypoglycaemia was recorded in 1513 of 9318 (16.2%) admitted LGA (defined as birthweight > or = 97.7 percentile) full-term neonates without maternal diabetes, of whom 20 (1.3%) had seizures. In six of these 20, hypoglycaemia was the single cause of seizures. CONCLUSION: Symptomatic hypoglycaemia occurs in healthy LGA full-term neonates.