速度向量成像技术评价冠心病心肌缺血患者节段心肌收缩功能的初步研究

目的应用速度向量成像(VVI)技术比较静息状态下相同节段的正常心肌及缺血心肌纵向和径向的运动特点,评价VⅥ技术对冠心病患者节段心肌收缩功能的临床价值。方法选取健康志愿者30例和冠心病心肌缺血患者30例,分别为健康对照组与观察组。观察心尖四腔、二腔和左室长轴切面,室壁均分为基底段、中间段、心尖段等3个节段;胸骨旁短轴切面二尖瓣水平、乳头肌水平、近心尖部水平3个短轴切面水平节段,分别测量缺血节段及正常节段的心肌速度(Vs)、应变(ε)和应变率(SR)。结果健康对照组左心室各室壁心尖段、中间段和基底段Vs依次递增(P<0.05);ε、SR差异无统计学意义(P>0.05);左心室各室壁近心尖水平、乳头肌水平以及二尖瓣水平径向Vs、ε、SR差异无统计学意义(P>0.05)。观察组缺血节段与健康对照组相比VVI测值降低(P<0.05)。血供正常节段与健康对照组相比VVI测值无显著差异(P>0.05)。结论 VVI技术可以作为无创冠心病诊断指标,有助于确定或排除冠心病诊断。

The preliminary stduy on evaluate the segmental myocardial systolic function of coronary artery disease by velocity vector imaging

Objective To use the character of velocity vector imaging（VVI） technology is relatively the same as the resting state of normal myocardial segments and ischemic myocardial longitudinal and radial movement characteristics,evaluation VVI technology segments of coronary heart disease clinical value of myocardial contractile function.Methods Thirty healthy volunteers and thirty patients with coronary artery disease were selected,and were divided into the normal group and the myocardial ischemia group.In apical four-chamber views,apical two-chamber views,apical left ventricular long axis views,each of ventricular wall is divided into basal segment,middle segment and apical segment,altogether 3 segments and so on;parasternal short axis views of papillary level,papillary muscle level and nearly apical level,each short axis views level segments were selected also.Quantitative analysis velocity（Vs）,strain（e）,strain rate（SR） about ischemic segments and normal segments.Results From basal segment to apex,the Vs gradient descent,but the SR and e were the same.Radial velocity,strain rate and strain among the different walls of the left ventricle are the same.When myocardial presented ischemic,lesion segments＇ VVI values decreased.Conclusion This research indicates that WI can be used as non-invasive diagnosis of coronary artery disease,which can help to identify or exclude the diagnosis of coronary artery disease.