Bilateral primary xanthoma of the humeri with pathologic fractures: A case report |
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Authors: | Sayed Ali Alex Fedenko Ali B Syed George Matcuk Dakshesh Patel Chris Gottsegen Eric White |
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Affiliation: | Sayed Ali, Ali B Syed, Department of Radiology, Temple University Hospital, 3401 N. Broad St. Philadelphia, PA 19140, United StatesAlex Fedenko, Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, United StatesGeorge Matcuk, Dakshesh Patel, Chris Gottsegen, Eric White, Department of Radiology, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, United States |
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Abstract: | Xanthomas are rare bone tumors that occur more often in the appendicular skeleton and typically appear radiographically benign, with a narrow zone of transition and a sclerotic rim. We report the case of a 57-year-old woman with hyperlipidemia presenting with bilateral shoulder pain after minor trauma. Radiographic and histopathologic investigation demonstrated intraosseous xanthoma with atypical features, including multifocality, a wide zone of transition and pathologic fractures-characteristics more commonly associated with aggressive lesions such as multiple myeloma or metastasis. The diagnosis, imaging, and histological appearance of xanthoma of bone are reviewed. |
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Keywords: | Xanthoma Hyperlipidemia Pathologic fracture |
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