奇异值在评价舒张早期左心室流入血流中的应用

目的 探讨奇异值方法的左心室流入血流彩色多普勒信号特征,评估左室舒张功能变化.方法 选择左室舒张功能降低的各类心脏病患者163例,其中冠心病心肌梗死37例,冠心病心绞痛35例,扩张型心肌病45例,高血压46例,对照组30例.采用自制彩色多普勒超声分析系统,对舒张早期的左室血流图像进行彩色血流的色阶变化分析,自动显示与计算左室彩色血流传播速度的奇异值斜率(CV)与奇异值积分(AV).结果 左室舒张功能减低的心肌梗死、扩张型心肌病、心绞痛、高血压各组患者在所采集的舒张早期左室流人血流面积中,彩色血流奇异值CV(平均1.67～1.90)与奇异值AV(-0.11～-0.20)的绝对值均较对照组CV(2.40±0.22)、AV(-0.25±0.05)明显减小,差异具有统计学意义(P<0.001).结论 奇异值可反映左室彩色多普勒流入血流色阶差的变化,奇异值CV与奇异值AV能提示左室舒张功能的异常.

Preliminary application of diastolic inflow inside left ventricle using color singular value

Objective To develop a new method for describe features of inflow of left ventricle(LV) from color Doppler image by color singular value,and evaluat the value of color singular value in assessment of diastolic dysfunction. Methods Patients with diastolic dysfunction of LV including myocardial infarction (n = 37), angina( n = 35), cardiomyopathy( n = 45) and hypertension ( n =46) were selected and 30 healthy cases as control. CV and AV from color singular value of LV inflow was displayed and calculated automatically by an analyzing system developed in our laboratory. Results Compared with that of control (CV:2.40 0.22 and AV: -0.25 0.05), the absolute value of CV(1.67-1.90 in average)and AV( - 0. 11～-0. 20 in average) from color singular value were decreased significantly( P <0. 001) in groupsof myocardial infarction, angina, cardiomyopathy and hypertension. Conclusions Singular value can be applied to detect color differences in LV inflow from color Doppler signals. Changes of singular value within the diastolic inflow under pathological conditions may reflect the diastolic dysfunction of LV.